DE is a direct replica of SGT 78 (also known as CUMYL-CYBINACA or CUMYL-4CN-BINACA) is an indazole-3-carboxamide based synthetic cannabinoid that has been sold online as a designer drug. While the in vitro activity of this compound is not disclosed in the associated patent, anecdotal reports suggest it is a potent cannabinoid agonist with an active dose of around 0.1mg.
DE & SGT-78 cannabinoid (or 4-CN-CUMYL-BUTINACA) is based on anindazole core structure where the 1- and 3- positions of the indazole ring system are substituted. The 1- position of 4-CN-CUMYL-BUTINACA is substituted with a linear four carbon chain terminated with a cyano (CN) group. The 3- position is substituted with an amide linker, andthe nitrogen atom (N) of this linker is further substituted with a2-phenyl-propan-2-yl group.
Research shows that SGT-78 delivers intense physiological and psychoactive effects, and has a high affinity for binding with cannabinoid receptors CB1 and CB2, but it favors CB1 receptors. If you compare SGT-78 with its closest relative, SGT-25 (5F-CUMYL-PINACA), researchers have reported that SGT-78 is more potent, forming a much tighter bind with the cannabinoid receptors
Formal Name :1-(4-cyanobutyl)-N-(2-phenylpropan-2-yl)-1H-indazole-3-carboxamide
Chemical Formula: C22H24N4O
Exact Mass: 360.20
Molecular Weight: 360.46
SGT-78 is also found listed on-line under the following names:
- 4-CN BINACA-ADB
- 4-CN CUMYL-BINACA
- 4-CN-CUMYL-BUTINACA
- CUMYL-4CN-BINACA
- CUMYL-CB-PINACA
- CUMYL-CYBINACA
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